Phylogenetic distinction of iNOS and IDO function in mesenchymal stem cell-mediated immunosuppression in mammalian species

Mammalian mesenchymal stem cells (MSCs) have been shown to be strongly immunosuppressive in both animal disease models and human clinical trials. We have reported that the key molecule mediating immunosuppression by MSCs is species dependent: indoleamine 2,3-dioxygenase (IDO) in human and inducible...

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Detalles Bibliográficos
Autores principales: Su, J, Chen, X, Huang, Y, Li, W, Li, J, Cao, K, Cao, G, Zhang, L, Li, F, Roberts, A I, Kang, H, Yu, P, Ren, G, Ji, W, Wang, Y, Shi, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921585/
https://www.ncbi.nlm.nih.gov/pubmed/24162664
http://dx.doi.org/10.1038/cdd.2013.149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921585/
https://www.ncbi.nlm.nih.gov/pubmed/24162664
http://dx.doi.org/10.1038/cdd.2013.149

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