Targeting the Endocannabinoid System for Neuroprotection: A (19)F-NMR Study of a Selective FAAH Inhibitor Binding with an Anandamide Carrier Protein, HSA

Fatty acid amide hydrolase (FAAH), the enzyme involved in the inactivation of the endocannabinoid anandamide (AEA), is being considered as a therapeutic target for analgesia and neuroprotection. We have developed a brain permeable FAAH inhibitor, AM5206, which has served as a valuable pharmacologica...

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Detalles Bibliográficos
Autores principales: Zhuang, Jianqin, Yang, De-Ping, Tian, Xiaoyu, Nikas, Spyros P., Sharma, Rishi, Guo, Jason Jianxin, Makriyannis, Alexandros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921897/
https://www.ncbi.nlm.nih.gov/pubmed/24533425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921897/
https://www.ncbi.nlm.nih.gov/pubmed/24533425

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