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Inflammatory stimulation preserves physiological properties of retinal ganglion cells after optic nerve injury

Axonal injury in the optic nerve is associated with retinal ganglion cell (RGC) degeneration and irreversible loss of vision. However, inflammatory stimulation (IS) by intravitreal injection of Pam(3)Cys transforms RGCs into an active regenerative state enabling these neurons to survive injury and t...

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Detalles Bibliográficos
Autores principales: Stutzki, Henrike, Leibig, Christian, Andreadaki, Anastasia, Fischer, Dietmar, Zeck, Günther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922046/
https://www.ncbi.nlm.nih.gov/pubmed/24574973
http://dx.doi.org/10.3389/fncel.2014.00038