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NitroDIGE analysis reveals inhibition of protein S-nitrosylation by epigallocatechin gallates in lipopolysaccharide-stimulated microglial cells

BACKGROUND: Nitric oxide (NO) is a signaling molecule regulating numerous cellular functions in development and disease. In the brain, neuronal injury or neuroinflammation can lead to microglial activation, which induces NO production. NO can react with critical cysteine thiols of target proteins fo...

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Detalles Bibliográficos
Autores principales: Qu, Zhe, Meng, Fanjun, Zhou, Hui, Li, Jilong, Wang, Quanhui, Wei, Fan, Cheng, Jianlin, Greenlief, C Michael, Lubahn, Dennis B, Sun, Grace Y, Liu, Siqi, Gu, Zezong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922161/
https://www.ncbi.nlm.nih.gov/pubmed/24472655
http://dx.doi.org/10.1186/1742-2094-11-17