Adaptation of leukemia cells to hypoxic condition through switching the energy metabolism or avoiding the oxidative stress

BACKGROUND: Like normal hematopoietic stem cells, leukemia cells proliferate in bone marrow, where oxygen supply is limited. However, the growth and energy metabolism of leukemia cells under hypoxia have not been well understood. Although it has been known that reactive oxygen species (ROS) is gener...

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Detalles Bibliográficos
Autores principales: Goto, Mineaki, Miwa, Hiroshi, Suganuma, Kazuto, Tsunekawa-Imai, Norikazu, Shikami, Masato, Mizutani, Motonori, Mizuno, Shohei, Hanamura, Ichiro, Nitta, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922169/
https://www.ncbi.nlm.nih.gov/pubmed/24506813
http://dx.doi.org/10.1186/1471-2407-14-76

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922169/
https://www.ncbi.nlm.nih.gov/pubmed/24506813
http://dx.doi.org/10.1186/1471-2407-14-76

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