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The kinetochore protein Cenp-F is a potential novel target for zoledronic acid in breast cancer cells

The anti-resorptive agent zoledronic acid inhibits key enzymes in the mevalonate pathway, disrupting post-translational modification and thereby correct protein localization and function. Inhibition of prenylation may also be responsible for the reported anti-tumour effects of zoledronic acid, but t...

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Detalles Bibliográficos
Autores principales: Brown, Hannah K, Ottewell, Penelope D, Coleman, Robert E, Holen, Ingunn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922372/
https://www.ncbi.nlm.nih.gov/pubmed/20015195
http://dx.doi.org/10.1111/j.1582-4934.2009.00995.x