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The kinetochore protein Cenp-F is a potential novel target for zoledronic acid in breast cancer cells
The anti-resorptive agent zoledronic acid inhibits key enzymes in the mevalonate pathway, disrupting post-translational modification and thereby correct protein localization and function. Inhibition of prenylation may also be responsible for the reported anti-tumour effects of zoledronic acid, but t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922372/ https://www.ncbi.nlm.nih.gov/pubmed/20015195 http://dx.doi.org/10.1111/j.1582-4934.2009.00995.x |