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Early long-term L-T3 replacement rescues mitochondria and prevents ischemic cardiac remodelling in rats

3,5,3′-Levo-triiodothyronine (L-T3) is essential for DNA transcription, mitochondrial biogenesis and respiration, but its circulating levels rapidly decrease after myocardial infarction (MI). The main aim of our study was to test whether an early and sustained normalization of L-T3 serum levels afte...

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Detalles Bibliográficos
Autores principales: Forini, Francesca, Lionetti, Vincenzo, Ardehali, Hossein, Pucci, Angela, Cecchetti, Federica, Ghanefar, Mohsen, Nicolini, Giuseppina, Ichikawa, Yoshihiko, Nannipieri, Monica, Recchia, Fabio A, Iervasi, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922373/
https://www.ncbi.nlm.nih.gov/pubmed/20100314
http://dx.doi.org/10.1111/j.1582-4934.2010.01014.x