A shotgun antisense approach to the identification of novel essential genes in Pseudomonas aeruginosa

BACKGROUND: Antibiotics in current use target a surprisingly small number of cellular functions: cell wall, DNA, RNA, and protein biosynthesis. Targeting of novel essential pathways is expected to play an important role in the discovery of new antibacterial agents against bacterial pathogens, such a...

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Detalles Bibliográficos
Autores principales: Rusmini, Ruggero, Vecchietti, Davide, Macchi, Raffaella, Vidal-Aroca, Faustino, Bertoni, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922391/
https://www.ncbi.nlm.nih.gov/pubmed/24499134
http://dx.doi.org/10.1186/1471-2180-14-24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922391/
https://www.ncbi.nlm.nih.gov/pubmed/24499134
http://dx.doi.org/10.1186/1471-2180-14-24

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