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A shotgun antisense approach to the identification of novel essential genes in Pseudomonas aeruginosa
BACKGROUND: Antibiotics in current use target a surprisingly small number of cellular functions: cell wall, DNA, RNA, and protein biosynthesis. Targeting of novel essential pathways is expected to play an important role in the discovery of new antibacterial agents against bacterial pathogens, such a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922391/ https://www.ncbi.nlm.nih.gov/pubmed/24499134 http://dx.doi.org/10.1186/1471-2180-14-24 |