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Influence networks based on coexpression improve drug target discovery for the development of novel cancer therapeutics

BACKGROUND: The demand for novel molecularly targeted drugs will continue to rise as we move forward toward the goal of personalizing cancer treatment to the molecular signature of individual tumors. However, the identification of targets and combinations of targets that can be safely and effectivel...

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Detalles Bibliográficos
Autores principales: Penrod, Nadia M, Moore, Jason H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922430/
https://www.ncbi.nlm.nih.gov/pubmed/24495353
http://dx.doi.org/10.1186/1752-0509-8-12