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Partial deficiency of HIF-1α stimulates pathological cardiac changes in streptozotocin-induced diabetic mice
BACKGROUND: Diabetic cardiomyopathy is associated with a number of functional and structural pathological changes such as left ventricular dysfunction, cardiac remodeling, and apoptosis. The primary cause of diabetic cardiomyopathy is hyperglycemia, the metabolic hallmark of diabetes. Recent studies...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922431/ https://www.ncbi.nlm.nih.gov/pubmed/24502509 http://dx.doi.org/10.1186/1472-6823-14-11 |