Cargando…

Partial deficiency of HIF-1α stimulates pathological cardiac changes in streptozotocin-induced diabetic mice

BACKGROUND: Diabetic cardiomyopathy is associated with a number of functional and structural pathological changes such as left ventricular dysfunction, cardiac remodeling, and apoptosis. The primary cause of diabetic cardiomyopathy is hyperglycemia, the metabolic hallmark of diabetes. Recent studies...

Descripción completa

Detalles Bibliográficos
Autores principales: Bohuslavova, Romana, Kolar, Frantisek, Sedmera, David, Skvorova, Lada, Papousek, Frantisek, Neckar, Jan, Pavlinkova, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922431/
https://www.ncbi.nlm.nih.gov/pubmed/24502509
http://dx.doi.org/10.1186/1472-6823-14-11