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The novel arylindolylmaleimide PDA-66 displays pronounced antiproliferative effects in acute lymphoblastic leukemia cells

BACKGROUND: Prognosis of adult patients suffering from acute lymphoblastic leukemia (ALL) is still unsatisfactory. Targeted therapy via inhibition of deregulated signaling pathways appears to be a promising therapeutic option for the treatment of ALL. Herein, we evaluated the influence of a novel ar...

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Detalles Bibliográficos
Autores principales: Kretzschmar, Christin, Roolf, Catrin, Langhammer, Tina-Susann, Sekora, Anett, Pews-Davtyan, Anahit, Beller, Matthias, Frech, Moritz J, Eisenlöffel, Christian, Rolfs, Arndt, Junghanss, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922486/
https://www.ncbi.nlm.nih.gov/pubmed/24502201
http://dx.doi.org/10.1186/1471-2407-14-71