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Age-dependent defective TGF-beta1 signaling in patients undergoing coronary artery bypass grafting
BACKGROUND: Transforming growth factor beta (TGF-β1) is a pleiotropic cytokine, which is deregulated in atherosclerosis; however the role of age in this process is unknown. We aimed to assess whether TGF-β1 signaling is affected by age. METHODS: Vascular smooth muscle cells (VSMC) were obtained from...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922540/ https://www.ncbi.nlm.nih.gov/pubmed/24495866 http://dx.doi.org/10.1186/1749-8090-9-24 |