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Effects of Dexamethasone on Mesenchymal Stromal Cell Chondrogenesis and Aggrecanase Activity: Comparison of Agarose and Self-Assembling Peptide Scaffolds

OBJECTIVE: Dexamethasone (Dex) is a synthetic glucocorticoid that has pro-anabolic and anticatabolic effects in cartilage tissue engineering systems, though the mechanisms by which these effects are mediated are not well understood. We tested the hypothesis that the addition of Dex to chondrogenic m...

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Detalles Bibliográficos
Autores principales: Florine, Emily M., Miller, Rachel E., Porter, Ryan M., Evans, Christopher H., Kurz, Bodo, Grodzinsky, Alan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922645/
https://www.ncbi.nlm.nih.gov/pubmed/24533173
http://dx.doi.org/10.1177/1947603512455196