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Effects of Dexamethasone on Mesenchymal Stromal Cell Chondrogenesis and Aggrecanase Activity: Comparison of Agarose and Self-Assembling Peptide Scaffolds
OBJECTIVE: Dexamethasone (Dex) is a synthetic glucocorticoid that has pro-anabolic and anticatabolic effects in cartilage tissue engineering systems, though the mechanisms by which these effects are mediated are not well understood. We tested the hypothesis that the addition of Dex to chondrogenic m...
Autores principales: | Florine, Emily M., Miller, Rachel E., Porter, Ryan M., Evans, Christopher H., Kurz, Bodo, Grodzinsky, Alan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922645/ https://www.ncbi.nlm.nih.gov/pubmed/24533173 http://dx.doi.org/10.1177/1947603512455196 |
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