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SKAP2, a novel target of HSF4b, associates with NCK2/F-actin at membrane ruffles and regulates actin reorganization in lens cell

In addition to roles in stress response, heat shock factors (HSFs) play crucial roles in differentiation and development. Heat shock transcription factor 4 (HSF4) deficiency leads to defect in lens epithelial cell (LEC) differentiation and cataract formation. However, the mechanism remains obscure....

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Detalles Bibliográficos
Autores principales: Zhou, Li, Zhang, Zhenguo, Zheng, Yufang, Zhu, Yufei, Wei, Zejun, Xu, Heng, Tang, Quan, Kong, Xiangyin, Hu, Landian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922667/
https://www.ncbi.nlm.nih.gov/pubmed/20219016
http://dx.doi.org/10.1111/j.1582-4934.2010.01048.x