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SKAP2, a novel target of HSF4b, associates with NCK2/F-actin at membrane ruffles and regulates actin reorganization in lens cell
In addition to roles in stress response, heat shock factors (HSFs) play crucial roles in differentiation and development. Heat shock transcription factor 4 (HSF4) deficiency leads to defect in lens epithelial cell (LEC) differentiation and cataract formation. However, the mechanism remains obscure....
Autores principales: | Zhou, Li, Zhang, Zhenguo, Zheng, Yufang, Zhu, Yufei, Wei, Zejun, Xu, Heng, Tang, Quan, Kong, Xiangyin, Hu, Landian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922667/ https://www.ncbi.nlm.nih.gov/pubmed/20219016 http://dx.doi.org/10.1111/j.1582-4934.2010.01048.x |
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