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Connexin 43 mimetic peptide Gap27 reveals potential differences in the role of Cx43 in wound repair between diabetic and non-diabetic cells

During early wound healing (WH) events Connexin 43 (Cx43) is down-regulated at wound margins. In chronic wound margins, including diabetic wounds, Cx43 expression is enhanced suggesting that down-regulation is important for WH. We previously reported that the Cx43 mimetic peptide Gap27 blocks Cx43 m...

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Detalles Bibliográficos
Autores principales: Pollok, Simone, Pfeiffer, Ann-Catherine, Lobmann, Ralf, Wright, Catherine S, Moll, Ingrid, Martin, Patricia E M, Brandner, Johanna M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922673/
https://www.ncbi.nlm.nih.gov/pubmed/20345849
http://dx.doi.org/10.1111/j.1582-4934.2010.01057.x