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A Genetic Variant in Vitamin B12 Metabolic Genes That Reduces the Risk of Congenital Heart Disease in Han Chinese Populations

BACKGROUND: Genome-wide association studies on components of the one-carbon metabolic pathway revealed that human vitamin B12 levels could be significantly influenced by variationsinthefucosyltransferase 2 (FUT2), cubilin (CUBN), and transcobalamin-I (TCN1) genes. An altered vitamin B12 level is an...

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Detalles Bibliográficos
Autores principales: Wang, Jue, Zhao, Jian-Yuan, Wang, Feng, Peng, Qian-Qian, Hou, Jia, Sun, Shu-Na, Gui, Yong-Hao, Duan, Wen-Yuan, Qiao, Bin, Wang, Hong-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922769/
https://www.ncbi.nlm.nih.gov/pubmed/24533076
http://dx.doi.org/10.1371/journal.pone.0088332