The innate immune system as mediator of systemic DNA damage responses

DNA damage causally contributes to cancer development and tissue degeneration with aging.(1) Cellular DNA damage responses (DDR) mediate cell cycle arrest to allow time for DNA repair, or induce cellular senescence and apoptosis to eliminate damaged cells.(2) In contrast to cell-autonomous DNA damag...

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Detalles Bibliográficos
Autores principales: Ermolaeva, Maria, Schumacher, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Article Addendum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922787/
https://www.ncbi.nlm.nih.gov/pubmed/25210580
http://dx.doi.org/10.4161/cib.26926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922787/
https://www.ncbi.nlm.nih.gov/pubmed/25210580
http://dx.doi.org/10.4161/cib.26926

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