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Changes in the pharmacokinetic of sildenafil citrate in rats with Streptozotocin-induced diabetic nephropathy

AIM: The present investigates deals with the change in the pharmacokinetic of Sildenafil citrate (SIL) in disease condition like diabetic nephropathy (DN). METHOD: Diabetes was induced in rats by administering Streptozotocin i.e. STZ (60 mg/kg, IP) saline solution. Assessment of diabetes was done by...

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Detalles Bibliográficos
Autores principales: Tripathi, Alok S, Mazumder, Papiya M, Chandewar, Anil V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922855/
https://www.ncbi.nlm.nih.gov/pubmed/24398037
http://dx.doi.org/10.1186/2251-6581-13-8