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Analysis of early phase and subsequent phase III stroke studies of neuroprotectants: outcomes and predictors for success
BACKGROUND: Efficacy of neuroprotective treatments for ischemic stroke was not convincingly demonstrated in clinical phase III trials so far, whereas some preceding early phase studies found neuroprotection to be beneficial. We aimed to determine the frequency with which phase III studies are preced...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922860/ https://www.ncbi.nlm.nih.gov/pubmed/24502346 http://dx.doi.org/10.1186/2040-7378-6-2 |