RhoC Regulates Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma by Overexpressing IL-6 and Phosphorylation of STAT3

In this study we investigated the correlation between RhoC expression and cancer stem cells (CSCs) formation in head and neck squamous cell carcinoma (HNSCC). The inhibition of RhoC function was achieved using shRNA. The expression of stem cell surface markers, ALDH and CD44 were significantly low i...

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Detalles Bibliográficos
Autores principales: Islam, Mozaffarul, Sharma, Smita, Teknos, Theodoros N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922885/
https://www.ncbi.nlm.nih.gov/pubmed/24533098
http://dx.doi.org/10.1371/journal.pone.0088527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922885/
https://www.ncbi.nlm.nih.gov/pubmed/24533098
http://dx.doi.org/10.1371/journal.pone.0088527

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