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Microbial exposure alters HIV-1-induced mucosal CD4(+) T cell death pathways Ex vivo

BACKGROUND: Early HIV-1 infection causes massive CD4+ T cell death in the gut and translocation of bacteria into the circulation. However, the programmed cell death (PCD) pathways used by HIV-1 to kill CD4+ T cells in the gut, and the impact of microbial exposure on T cell loss, remain unclear. Unde...

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Detalles Bibliográficos
Autores principales: Steele, Amanda K, Lee, Eric J, Manuzak, Jennifer A, Dillon, Stephanie M, Beckham, John David, McCarter, Martin D, Santiago, Mario L, Wilson, Cara C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922902/
https://www.ncbi.nlm.nih.gov/pubmed/24495380
http://dx.doi.org/10.1186/1742-4690-11-14