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Microbial exposure alters HIV-1-induced mucosal CD4(+) T cell death pathways Ex vivo
BACKGROUND: Early HIV-1 infection causes massive CD4+ T cell death in the gut and translocation of bacteria into the circulation. However, the programmed cell death (PCD) pathways used by HIV-1 to kill CD4+ T cells in the gut, and the impact of microbial exposure on T cell loss, remain unclear. Unde...
Autores principales: | Steele, Amanda K, Lee, Eric J, Manuzak, Jennifer A, Dillon, Stephanie M, Beckham, John David, McCarter, Martin D, Santiago, Mario L, Wilson, Cara C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922902/ https://www.ncbi.nlm.nih.gov/pubmed/24495380 http://dx.doi.org/10.1186/1742-4690-11-14 |
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