Effects of Various Phytochemicals on Indoleamine 2,3-Dioxygenase 1 Activity: Galanal Is a Novel, Competitive Inhibitor of the Enzyme

Indoleamine 2,3-dioxygenase (IDO) 1, that catalyzes the first and rate-limiting step in the degradation of L-tryptophan, has an important immunomodulatory function. The activity of IDO1 increases in various inflammatory diseases, including tumors, autoimmune diseases, and different kinds of inflamma...

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Detalles Bibliográficos
Autores principales: Yamamoto, Rie, Yamamoto, Yasuko, Imai, Shinjiro, Fukutomi, Ryuta, Ozawa, Yoshio, Abe, Masako, Matuo, Yushi, Saito, Kuniaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923053/
https://www.ncbi.nlm.nih.gov/pubmed/24533148
http://dx.doi.org/10.1371/journal.pone.0088789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923053/
https://www.ncbi.nlm.nih.gov/pubmed/24533148
http://dx.doi.org/10.1371/journal.pone.0088789

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