Cargando…

HCV Core Residues Critical for Infectivity Are Also Involved in Core-NS5A Complex Formation

Hepatitis C virus (HCV) infection is a major cause of liver disease. The molecular machinery of HCV assembly and particle release remains obscure. A better understanding of the assembly events might reveal new potential antiviral strategies. It was suggested that the nonstructural protein 5A (NS5A),...

Descripción completa

Detalles Bibliográficos
Autores principales: Gawlik, Katarzyna, Baugh, James, Chatterji, Udayan, Lim, Precious J., Bobardt, Michael D., Gallay, Philippe A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923060/
https://www.ncbi.nlm.nih.gov/pubmed/24533158
http://dx.doi.org/10.1371/journal.pone.0088866