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Cycle Length Restitution in Sinoatrial Node Cells: A Theory for Understanding Spontaneous Action Potential Dynamics

Normal heart rhythm (sinus rhythm) is governed by the sinoatrial node, a specialized and highly heterogeneous collection of spontaneously active myocytes in the right atrium. Sinoatrial node dysfunction, characterized by slow and/or asynchronous pacemaker activity and even failure, is associated wit...

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Detalles Bibliográficos
Autores principales: Glynn, Patric, Onal, Birce, Hund, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923067/
https://www.ncbi.nlm.nih.gov/pubmed/24533169
http://dx.doi.org/10.1371/journal.pone.0089049