Aggregate-Depleted Brain Fails to Induce Aβ Deposition in a Mouse Model of Alzheimer's Disease

Recent studies in animal models of Alzheimer's disease (AD) show that amyloid-beta (Aβ) misfolding can be transmissible; however, the mechanisms by which this process occurs have not been fully explored. The goal of this study was to analyze whether depletion of aggregates from an AD brain supp...

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Detalles Bibliográficos
Autores principales: Duran-Aniotz, Claudia, Morales, Rodrigo, Moreno-Gonzalez, Ines, Hu, Ping Ping, Fedynyshyn, Joseph, Soto, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923072/
https://www.ncbi.nlm.nih.gov/pubmed/24533166
http://dx.doi.org/10.1371/journal.pone.0089014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923072/
https://www.ncbi.nlm.nih.gov/pubmed/24533166
http://dx.doi.org/10.1371/journal.pone.0089014

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