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Aggregate-Depleted Brain Fails to Induce Aβ Deposition in a Mouse Model of Alzheimer's Disease

Recent studies in animal models of Alzheimer's disease (AD) show that amyloid-beta (Aβ) misfolding can be transmissible; however, the mechanisms by which this process occurs have not been fully explored. The goal of this study was to analyze whether depletion of aggregates from an AD brain supp...

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Detalles Bibliográficos
Autores principales:	Duran-Aniotz, Claudia, Morales, Rodrigo, Moreno-Gonzalez, Ines, Hu, Ping Ping, Fedynyshyn, Joseph, Soto, Claudio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923072/ https://www.ncbi.nlm.nih.gov/pubmed/24533166 http://dx.doi.org/10.1371/journal.pone.0089014

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