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Accounting for centre-effects in multicentre trials with a binary outcome – when, why, and how?
BACKGROUND: It is often desirable to account for centre-effects in the analysis of multicentre randomised trials, however it is unclear which analysis methods are best in trials with a binary outcome. METHODS: We compared the performance of four methods of analysis (fixed-effects models, random-effe...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923100/ https://www.ncbi.nlm.nih.gov/pubmed/24512175 http://dx.doi.org/10.1186/1471-2288-14-20 |