The DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome

After undergoing massive RNA and protein rearrangements during assembly, the spliceosome undergoes a final, more subtle, ATP-dependent rearrangement that is essential for catalysis. This rearrangement requires the DEAH-box protein Prp2p, an RNA-dependent ATPase. Prp2p has been implicated in destabil...

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Detalles Bibliográficos
Autores principales: Wlodaver, Alissa M., Staley, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923124/
https://www.ncbi.nlm.nih.gov/pubmed/24442613
http://dx.doi.org/10.1261/rna.042598.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923124/
https://www.ncbi.nlm.nih.gov/pubmed/24442613
http://dx.doi.org/10.1261/rna.042598.113

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