Cellular mRNAs access second ORFs using a novel amino acid sequence-dependent coupled translation termination–reinitiation mechanism

Polycistronic transcripts are considered rare in the human genome. Initiation of translation of internal ORFs of eukaryotic genes has been shown to use either leaky scanning or highly structured IRES regions to access initiation codons. Studies on mammalian viruses identified a mechanism of coupled...

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Detalles Bibliográficos
Autores principales: Gould, Phillip S., Dyer, Nigel P., Croft, Wayne, Ott, Sascha, Easton, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923131/
https://www.ncbi.nlm.nih.gov/pubmed/24412912
http://dx.doi.org/10.1261/rna.041574.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923131/
https://www.ncbi.nlm.nih.gov/pubmed/24412912
http://dx.doi.org/10.1261/rna.041574.113

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