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Orexin 1 receptor antagonists in compulsive behavior and anxiety: possible therapeutic use

Fifteen years after the discovery of hypocretin/orexin a large body of evidence has been collected supporting its critical role in the modulation of several regulatory physiological functions. While reduced levels of hypocretin/orexin were initially associated with narcolepsy, increased levels have...

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Detalles Bibliográficos
Autores principales: Merlo Pich, Emilio, Melotto, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923148/
https://www.ncbi.nlm.nih.gov/pubmed/24592206
http://dx.doi.org/10.3389/fnins.2014.00026