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A lentiviral sponge for miR-101 regulates RanBP9 expression and amyloid precursor protein metabolism in hippocampal neurons

Neurodegeneration associated with amyloid β (Aβ) peptide accumulation, synaptic loss, and memory impairment are pathophysiological features of Alzheimer's disease (AD). Numerous microRNAs regulate amyloid precursor protein (APP) expression and metabolism. We previously reported that miR-101 is...

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Detalles Bibliográficos
Autores principales: Barbato, Christian, Pezzola, Silvia, Caggiano, Cinzia, Antonelli, Martina, Frisone, Paola, Ciotti, Maria Teresa, Ruberti, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923151/
https://www.ncbi.nlm.nih.gov/pubmed/24592211
http://dx.doi.org/10.3389/fncel.2014.00037