Human TP53 polymorphism (rs1042522) modelled in mouse does not affect glucose metabolism and body composition

Variation in TP53 has been associated with cancer. The pro-allele of a TP53 polymorphism in codon 72 (rs1042522) has been associated with longevity. Recently, we showed that the same allele might be involved in preservation of glucose metabolism, body composition and blood pressure during ageing. He...

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Detalles Bibliográficos
Autores principales: Reiling, Erwin, Speksnijder, Ewoud N., Pronk, Amanda C. M., van den Berg, Sjoerd A. A., Neggers, Silvia J. W., Rietbroek, Ilma, van Steeg, Harry, Dollé, Martijn E. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923217/
https://www.ncbi.nlm.nih.gov/pubmed/24522546
http://dx.doi.org/10.1038/srep04091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923217/
https://www.ncbi.nlm.nih.gov/pubmed/24522546
http://dx.doi.org/10.1038/srep04091

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