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Human TP53 polymorphism (rs1042522) modelled in mouse does not affect glucose metabolism and body composition
Variation in TP53 has been associated with cancer. The pro-allele of a TP53 polymorphism in codon 72 (rs1042522) has been associated with longevity. Recently, we showed that the same allele might be involved in preservation of glucose metabolism, body composition and blood pressure during ageing. He...
Autores principales: | Reiling, Erwin, Speksnijder, Ewoud N., Pronk, Amanda C. M., van den Berg, Sjoerd A. A., Neggers, Silvia J. W., Rietbroek, Ilma, van Steeg, Harry, Dollé, Martijn E. T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923217/ https://www.ncbi.nlm.nih.gov/pubmed/24522546 http://dx.doi.org/10.1038/srep04091 |
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