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Conserved Two-Step Regulatory Mechanism of Human Epithelial Differentiation

Human epithelia are organized in a hierarchical structure, where stem cells generate terminally differentiated cells via intermediate progenitors. This two-step differentiation process is conserved in all tissues, but it is not known whether a common gene set contributes to its regulation. Here, we...

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Detalles Bibliográficos
Autores principales: Rane, Jayant K., Droop, Alastair P., Pellacani, Davide, Polson, Euan S., Simms, Matthew S., Collins, Anne T., Caves, Leo S.D., Maitland, Norman J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923223/
https://www.ncbi.nlm.nih.gov/pubmed/24527392
http://dx.doi.org/10.1016/j.stemcr.2014.01.001