Cargando…

The human cap-binding complex is functionally connected to the nuclear RNA exosome

Nuclear processing and quality control of eukaryotic RNA is mediated by the RNA exosome, which is regulated by accessory factors. However, the mechanism of exosome recruitment to its ribonucleoprotein (RNP) targets remains poorly understood. Here we disclose a physical link between the human exosome...

Descripción completa

Detalles Bibliográficos
Autores principales: Andersen, Peter Refsing, Domanski, Michal, Kristiansen, Maiken S., Storvall, Helena, Ntini, Evgenia, Verheggen, Celine, Schein, Aleks, Bunkenborg, Jakob, Poser, Ina, Hallais, Marie, Sandberg, Rickard, Hyman, Anthony, LaCava, John, Rout, Michael P., Andersen, Jens S., Bertrand, Edouard, Jensen, Torben Heick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923317/
https://www.ncbi.nlm.nih.gov/pubmed/24270879
http://dx.doi.org/10.1038/nsmb.2703