Crosstalk between the Smad and the Mitogen-Activated Protein Kinase Pathways is Essential for Erythroid Differentiation of Erythroleukemia Cells Induced by TGF-β, Activin, Hydroxyurea and Butyrate

The role of crosstalk between the Smad and the MAPK signaling pathways in activin-, transforming growth factor-β (TGF-β)-, hydroxyurea (HU) - and butyrate-dependent erythroid differentiation of K562 leukemic cells was studied. Treatment with all four inducers caused transient phosphorylation of Smad...

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Detalles Bibliográficos
Autores principales: Akel, Salem, Bertolette, Daniel, Ruscetti, Francis W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923467/
https://www.ncbi.nlm.nih.gov/pubmed/24533426
http://dx.doi.org/10.4172/2329-6917.1000109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923467/
https://www.ncbi.nlm.nih.gov/pubmed/24533426
http://dx.doi.org/10.4172/2329-6917.1000109

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