CAPS and Munc13 utilize distinct PIP(2)-linked mechanisms to promote vesicle exocytosis

Phosphoinositides provide compartment-specific signals for membrane trafficking. Plasma membrane phosphatidylinositol 4,5-bisphosphate (PIP(2)) is required for Ca(2+)-triggered vesicle exocytosis, but whether vesicles fuse into PIP(2)-rich membrane domains in live cells and whether PIP(2) is metabol...

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Detalles Bibliográficos
Autores principales: Kabachinski, Greg, Yamaga, Masaki, Kielar-Grevstad, D. Michelle, Bruinsma, Stephen, Martin, Thomas F. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923642/
https://www.ncbi.nlm.nih.gov/pubmed/24356451
http://dx.doi.org/10.1091/mbc.E12-11-0829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923642/
https://www.ncbi.nlm.nih.gov/pubmed/24356451
http://dx.doi.org/10.1091/mbc.E12-11-0829

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