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CAPS and Munc13 utilize distinct PIP(2)-linked mechanisms to promote vesicle exocytosis
Phosphoinositides provide compartment-specific signals for membrane trafficking. Plasma membrane phosphatidylinositol 4,5-bisphosphate (PIP(2)) is required for Ca(2+)-triggered vesicle exocytosis, but whether vesicles fuse into PIP(2)-rich membrane domains in live cells and whether PIP(2) is metabol...
Autores principales: | Kabachinski, Greg, Yamaga, Masaki, Kielar-Grevstad, D. Michelle, Bruinsma, Stephen, Martin, Thomas F. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923642/ https://www.ncbi.nlm.nih.gov/pubmed/24356451 http://dx.doi.org/10.1091/mbc.E12-11-0829 |
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