Mathematical Model of a Telomerase Transcriptional Regulatory Network Developed by Cell-Based Screening: Analysis of Inhibitor Effects and Telomerase Expression Mechanisms

Cancer cells depend on transcription of telomerase reverse transcriptase (TERT). Many transcription factors affect TERT, though regulation occurs in context of a broader network. Network effects on telomerase regulation have not been investigated, though deeper understanding of TERT transcription re...

Descripción completa

Detalles Bibliográficos
Autores principales: Bilsland, Alan E., Stevenson, Katrina, Liu, Yu, Hoare, Stacey, Cairney, Claire J., Roffey, Jon, Keith, W. Nicol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923661/
https://www.ncbi.nlm.nih.gov/pubmed/24550717
http://dx.doi.org/10.1371/journal.pcbi.1003448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923661/
https://www.ncbi.nlm.nih.gov/pubmed/24550717
http://dx.doi.org/10.1371/journal.pcbi.1003448

Ejemplares similares