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Accurate and Robust Genomic Prediction of Celiac Disease Using Statistical Learning

Practical application of genomic-based risk stratification to clinical diagnosis is appealing yet performance varies widely depending on the disease and genomic risk score (GRS) method. Celiac disease (CD), a common immune-mediated illness, is strongly genetically determined and requires specific HL...

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Detalles Bibliográficos
Autores principales: Abraham, Gad, Tye-Din, Jason A., Bhalala, Oneil G., Kowalczyk, Adam, Zobel, Justin, Inouye, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923679/
https://www.ncbi.nlm.nih.gov/pubmed/24550740
http://dx.doi.org/10.1371/journal.pgen.1004137