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Deletion of the NSm Virulence Gene of Rift Valley Fever Virus Inhibits Virus Replication in and Dissemination from the Midgut of Aedes aegypti Mosquitoes

BACKGROUND: Previously, we investigated the role of the Rift Valley fever virus (RVFV) virulence genes NSs and NSm in mosquitoes and demonstrated that deletion of NSm significantly reduced the infection, dissemination, and transmission rates of RVFV in Aedes aegypti mosquitoes. The specific aim of t...

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Detalles Bibliográficos
Autores principales: Kading, Rebekah C., Crabtree, Mary B., Bird, Brian H., Nichol, Stuart T., Erickson, Bobbie Rae, Horiuchi, Kalanthe, Biggerstaff, Brad J., Miller, Barry R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923680/
https://www.ncbi.nlm.nih.gov/pubmed/24551252
http://dx.doi.org/10.1371/journal.pntd.0002670