Simultaneous Inhibition of the HGF/MET and Erk1/2 Pathways Affect Uveal Melanoma Cell Growth and Migration

PURPOSE: Nearly all primary uveal melanoma (UM) that metastasize involve the liver. Hepatocyte growth factor (HGF) is proposed to be an important microenvironmental element in attracting/supporting UM metastasis through activation of MET. The majority (>85%) of UM express mutations in the G-alpha...

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Detalles Bibliográficos
Autores principales: Chattopadhyay, Chandrani, Grimm, Elizabeth A., Woodman, Scott E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923717/
https://www.ncbi.nlm.nih.gov/pubmed/24551032
http://dx.doi.org/10.1371/journal.pone.0083957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923717/
https://www.ncbi.nlm.nih.gov/pubmed/24551032
http://dx.doi.org/10.1371/journal.pone.0083957

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