Matriptase Deletion Initiates a Sjögren’s Syndrome-Like Disease in Mice

OBJECTIVE: The objective of this study was to determine the effect of epithelial barrier disruption, caused by deficiency of the membrane-anchored serine protease, matriptase, on salivary gland function and the induction of autoimmunity in an animal model. METHODS: Embryonic and acute ablation of ma...

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Detalles Bibliográficos
Autores principales: Yin, Hongen, Kosa, Peter, Liu, Xibao, Swaim, William D., Lai, Zhennan, Cabrera-Perez, Javier, Di Pasquale, Giovanni, Ambudkar, Indu S., Bugge, Thomas H., Chiorini, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923742/
https://www.ncbi.nlm.nih.gov/pubmed/24551030
http://dx.doi.org/10.1371/journal.pone.0082852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923742/
https://www.ncbi.nlm.nih.gov/pubmed/24551030
http://dx.doi.org/10.1371/journal.pone.0082852

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