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Quantitative and Qualitative Deficits in Neonatal Lung-Migratory Dendritic Cells Impact the Generation of the CD8+ T Cell Response

CD103+ and CD11b+ populations of CD11c+MHCIIhi murine dendritic cells (DCs) have been shown to carry antigens from the lung through the afferent lymphatics to mediastinal lymph nodes (MLN). We compared the responses of these two DC populations in neonatal and adult mice following intranasal infectio...

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Detalles Bibliográficos
Autores principales: Ruckwardt, Tracy J., Malloy, Allison M. W., Morabito, Kaitlyn M., Graham, Barney S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923758/
https://www.ncbi.nlm.nih.gov/pubmed/24550729
http://dx.doi.org/10.1371/journal.ppat.1003934