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Competitive and Cooperative Interactions Mediate RNA Transfer from Herpesvirus Saimiri ORF57 to the Mammalian Export Adaptor ALYREF

The essential herpesvirus adaptor protein HVS ORF57, which has homologs in all other herpesviruses, promotes viral mRNA export by utilizing the cellular mRNA export machinery. ORF57 protein specifically recognizes viral mRNA transcripts, and binds to proteins of the cellular transcription-export (TR...

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Detalles Bibliográficos
Autores principales: Tunnicliffe, Richard B., Hautbergue, Guillaume M., Wilson, Stuart A., Kalra, Priti, Golovanov, Alexander P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923783/
https://www.ncbi.nlm.nih.gov/pubmed/24550725
http://dx.doi.org/10.1371/journal.ppat.1003907