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Prednisolone Attenuates Improvement of Cardiac and Skeletal Contractile Function and Histopathology by Lisinopril and Spironolactone in the mdx Mouse Model of Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is an inherited disease that causes striated muscle weakness. Recently, we showed therapeutic effects of the combination of lisinopril (L), an angiotensin converting enzyme (ACE) inhibitor, and spironolactone (S), an aldosterone antagonist, in mice lacking dystrophi...

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Detalles Bibliográficos
Autores principales: Janssen, Paul M. L., Murray, Jason D., Schill, Kevin E., Rastogi, Neha, Schultz, Eric J., Tran, Tam, Raman, Subha V., Rafael-Fortney, Jill A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923790/
https://www.ncbi.nlm.nih.gov/pubmed/24551095
http://dx.doi.org/10.1371/journal.pone.0088360